Melanoma – Most Dangerous Skin Cancer
- Summary: Arises from melanocytes; can metastasize quickly. Often looks like an irregular mole with asymmetry, border irregularity, color variation, diameter >6mm, or evolution (ABCDE rule).
- Prevention: Monthly self-skin exams, annual dermatologist checks, sun protection.
- Treatment: Early-stage requires surgical excision. Advanced melanoma may need immunotherapy (e.g., pembrolizumab), targeted therapy (e.g., BRAF inhibitors), or chemotherapy.

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